Kristine M. Talley, PhD, RN, GNP-BC

• Center Membership:
  Center for Aging Science and Care Innovation

My research focuses on identifying risk factors, prevention strategies, and treatments for late-life disability related to geriatric syndromes (i.e., urinary incontinence, frailty, falls, functional decline, and cognitive impairment) in frail older people. My research methods focus on quantitative analysis using longitudinal modeling, secondary dataset analyses, systematic literature reviews, and clinical trials.

Current Funded Research Projects:

Treatment of Clinical Alzheimer’s-type Dementia (CATD) and Diagnosis of CATD and Mild Cognitive Impairment (MCI)

PI: Howard Fink, Associate Professor of Medicine at the U of MN, MN EPC Associate Director

Role: Content Expert

Systematic review on diagnosis and treating Clinical Alzheimer’s-type Dementia (CATD) and Diagnosis of CATD and Mild Cognitive Impairment (MCI) with pharmacological and non-pharmacological strategies.

Funding source: Agency for Healthcare Research and Quality (AHRQ)

Restore: Improving sexual outcomes of gay and bisexual prostate cancer survivors

PI: Simon Rosser,Division of Epidemiology & Community Health, School of Public Health U of MN

Role: Co-I

This study will test the effects of a comprehensive, multi-component, online treatment program tailored for gay and bisexual prostate cancer survivors on their sexual and urinary functioning. It will also test new treatments for specific sexual consequences of prostate cancer treatment. If successful, the study will demonstrate that rehabilitation works for this population and establish a new standard of rehabilitation care for prostate cancer survivors.

Funding source: National Cancer Institute 1R01 CA218657-01

Adherence to Non-Group Based Exercise Interventions in Community-Dwelling Older Adults: Systematic Review and Meta-Analysis

Role: Co-PI with Dr. Jean F. Wyman

Systematic literature review identifying adherence rates and predictors of adherence to non-group based exercise interventions in community-dwelling older adults.

Funding source: School of Nursing Foundation

Urinary tract infections in adolescent girls and women: A claims-based analysis.

PI: Jean F. Wyman

Role: Co-I

Analyze claims data to identify the incidence and characteristics of adolescent girls and women with acute uncomplicated and recurrent urinary tract infections (UTI), construct and validate risk models to predict recurrent UTI in different age groups, and evaluate variations in diagnostic and treatment strategies in the treatment of acute uncomplicated UTI and how this affects subsequent UTI-related complications and resource utilization.

Funding source: School of Nursing Optum Lab credit

Selected Peer-Reviewed Publications:

Talley, K.M.C., Davis, N.D. & Wyman J. (2017). Determining a treatment plan for urinary incontinence in an older adult: Application of the four topic approach to ethical decision making. Urologic Nursing, 37(4), 181-203. DOI: 10.7257/1053-816X.2017.37.4.181

Whipple, M.O., Schorr, E.N., Talley, K.M.C., Lindquist, R., Bronas, U.G., & Treat-Jacobson, D. (2017). Variability in individual response to aerobic exercise interventions among older adults. Journal of Aging and Physical Activity, 1-37. doi:10.1123/japa.2017-0054. PMID: 28952853.

Whipple, M.O., Hamel, A., Talley, K.M.C. (2017). Fear of falling among community-dwelling older adults: A scoping review to identify effective evidence-based interventions. Geriatric Nursing.doi:10.1016/j.gerinurse.2017.08.005 PMID: 28941942

Talley, K.M.C., Wyman, J.F., Bronas, U, Olson-Kellogg, B., & McCarthy, T. (2017). Defeating urinary incontinence with exercise training: Results of a pilot study in frail older women. Journal of the American Geriatrics Society. doi 10.1111/jgs.14798, NIHMS837857

Talley, K.M.C., Wyman, J.F., Bronas, U, Olson-Kellogg, B., & McCarthy, T. (2016). Reliability and validity of two measures of toileting skills in frail older women without dementia. Journal of Gerontological Nursing, Epub ahead of print. doi:10.3928/00989134-20160531-02

Talley, K.M.C., Wyman, J.F., Savik, K., Kane, R.L., Mueller, C., & Zhao, H. (2015). Restorative care’s effect on activities of daily living dependency in long-stay nursing home residents. The Gerontologist, 55(Suppl 1), S88-98. doi:10.1093/geront/gnv011

Talley, K.M.C., Wyman, J.F., Gross, C.R., Lindquist, R.A., & Gaugler, J.E. (2014). Change in balance confidence and its associations with increasing disability in older community-dwelling women at risk for falling. Journal of Aging and Health, 26(4), 616-636. doi: 10.1177/0898264314526619

Talley, K.M.C., Wyman, J.F., Bronas, U.G., Olson-Kellogg, B.J., McCarthy, T.C., & Zhao, H. (2014). Factors associated with toileting disability in older adults without dementia living in residential care facilities. Nursing Research, 63(2), 94-104. doi: 10.1097/NNR.0000000000000017 NIHMS545046

Wang, S.I., Shamliyan, T.A., Talley, K.M.C., Ramakrishnan, R., & Kane, R.L. (2013). Not just specific diseases: Systematic review of the association of geriatric syndromes with hospitalization and nursing home admission. Archives of Gerontology and Geriatrics, 57(1), 16-26. doi:10.1016/j.archger.2013.03.007

Kane, R. L., Shamliyan, T., Talley, K., & Pacala, J. (2012). The association between geriatric syndromes and survival. Journal of the American Geriatrics Society, 60(5), 896-904. doi:10.1111/j.1532-5415.2012.03942.xPubMed PMID: 22568483.

Shamliyan, T., Talley, K. M. C., Ramakrishnan, R., & Kane, R. L. (2012). Association of frailty with survival: A systematic literature review. Ageing Research Reviews, 12(2), 719-736. doi:10.1016/j.arr.2012.03.001 PubMed PMID: 22426304.

Talley, K.M.C., Wyman, J.F., Shamliyan, T. (2011). State of the science: Conservative interventions for urinary incontinence in frail community-dwelling older adults. Nursing Outlook 59, 215-220.

McMahon, S., Talley, K.M.C., Wyman, J.F. (2011). Older People’s Perspectives on Fall Risk and Fall Prevention Programs: A Literature Review. International Journal of Nursing Older People 6(4): 289-298.

Kane, R.L., Talley, K.M.C., Shamliyan, T., and Pacala, J.T. (2011). Common Syndromes in Older Adults Related to Primary and Secondary Prevention. Evidence Report/Technology Assessment No. 87. AHRQ Publication No. 11-05157-EF-1. Rockville, MD. Agency for Healthcare Research and Quality; July 2011. Available at:http://www.uspreventiveservicestaskforce.org/uspstf11/es87.pdf

Butler, M., Talley, K.M.C., Burns, R., Ripley, A., Rothman, A., Johnson, P., Kane, R.A., and Kane, R.L. (2011) Values of Older Adults Related to Primary and Secondary Prevention. Evidence Synthesis No 84. AHRQ Publication No. 11-05154-EF-1, Rockville, MD, Agency for Healthcare Research and Quality; March 2011. Available at http://www.uspreventiveservicestaskforce.org/uspstf11/olderprev.pdf

Mueller, C., Goering, M., Talley, K.M.C., and Zaccagnini, M. (2011). “Taking on the Challenge of Clinical Teaching in Nursing Homes.” Journal of Gerontological Nursing 37(4).

Talley, K.M.C., Wyman, J.F. and Gross, C.R. (2008). Psychometric properties of the Activities-specific Balance Confidence Scale and the Survey of Activities and Fear of Falling in older women. Journal of the American Geriatrics Society 56(2), 328-333.

Lindquist, R., Wyman, J.F., Talley, K.M.C., Findorff, M. and Gross, C.R. (2007). Design of control conditions in clinical trials of behavioral interventions. Journal of Nursing Scholarship 39(3), 214-221.

Wyman, J.F., Croghan, CF., Nachreiner, N.M., Gross, C.R., Stock, H., Talley, K.M.C. and Monigold, M. (2007). Effectiveness of education and tailored counseling in reducing environmental hazards in the homes of community-dwelling older women. Journal of American Geriatrics Society 55(10), 1548-1556.