Casey Hooke, PhD, APRN, PCNS, CPON

Assistant Professor, School of Nursing

Casey Hooke

Contact Info

hook0035@umn.edu

Office Phone 612-624-2972

Fax 612-626-6606

Office Address:
6-117 Weaver-Densford Hall

Mailing Address:
School of Nursing
University of Minnesota
5-140 Weaver Densford Hall
308 Harvard St SE
Minneapolis, MN 55455

Assistant Professor, School of Nursing


Summary

Professional Associations

  • Co-operative Membership:
    Child and Family Health
  • Center Memberships:
    Center for Child and Family Health Promotion Research
    Center for Children with Special Health Care Needs
    University of Minnesota Cancer Center

Research

Research Summary/Interests

Children and adolescents with cancer: Symptom management, fatigue and related symptoms, physical performance, growth and development

Research Funding Grants

Research

Title of Project: Physical Activity in Children Completing Treatment for Leukemia Funding Agency: University of Minnesota/Olafson Trust Project Dates: 2016-2018 Role: Principal Investigator Overall Goals: 1. To explore the symptoms of fatigue, sleep disturbance, and cognitive in children with leukemia at the end of their treatment and examine if children who are more active, have less symptom distress and better quality of life; 2. To determine whether their biologic markers identified in the earlier study are predictive of their symptoms and quality of life at the end of treatment.

Title of Project: KAM: Kids are Moving; An Exercise Program for Children with Cancer. Funding Agency: Alex's Lemonade Stand Foundation Project Dates: 2015-2017 Role: Principal Investigator. Overall Goal: To evaluate the impact of an exercise program administered by pediatric oncology nurse practitioners during routine visits for children receiving cancer treatment at two pediatric oncology institutions.

Title of Project: Healthy Kids after Cancer; A Physical Activity and Nutrition Intervention. Funding Agency: NIH/NCI 5R21CA182727-02 Project Dates: 2014-2016 Role: Co-investigator Overall Goal: To evaluate the feasibility, acceptability, and potential efficacy of a parent-targeted, phone-delivered nutrition and physical activity program to prevent unhealthy weight gain among 60 childhood ALL survivors, 3-10 years of age.

Title of Project: Phenotype-Genotype Associations with Symptoms Clusters During Childhood Cancer Treatment Funding Agency: NIH/NCI 1R01CA169398-01 Project Dates: 2012-2017 Role: Co-investigator Overall goal: To examine biologic mechanisms that influence symptom toxicities caused by increased oxidative stress or cytokine production or actual failure of the anti-oxidant and anti-inflammatory defense systems due to genetic variation.

Title of Project: Palliative Cancer Care: Music Video for AYA-Parent Communication and Resilience Funding Agency: NIH/NCI 9R01 CA162181-05 Project Dates: 2011-2015 Role: Co-investigator Overall goal: To compare the efficacy of a therapeutic music video (TMV) with a TMV plus parent component (TMV+P) on outcomes for both adolescents and young adults (AYA) and their parents; and determine relationships of parent distress and parent perceived family environment with AYA outcomes.

Title of Project: Physical Activity and Fatigue in Children and Adolescents with Cancer. Funding Agency: St. Baldrick's Foundation Project Dates: 2010-2013 Role: Principal investigator Overall goal: To explore the measurement of physical activity and evaluate an activity intervention for children and adolescents undergoing cancer treatment.

Title of Project: Preliminary Content Validation Steps for the Pediatric Oncology Patient Self-Report CTCAE. Funding Agency: Alex's Lemonade Stand Foundation Project Dates: 2012-2013 Role: Co-investigator Overall goal: To complete a two-part content validation study with pediatric clinicians and researchers directly involved with pediatric oncology patients regarding items on the CTCAE for which the child or family caregiver proxy could be expected to provide descriptive responses.

Title of Project: Physical Activity and Fatigue in Children and Adolescents with Cancer Funding Agency: St Baldrick's Foundation Project Dates: 2010 to 2013 Role: Principal Investigator Overall goal: To explore the measurement of physical activity and evaluate an activity intervention for children and adolescents undergoing cancer treatment.

Title of Project: Yoga for Children and Adolescents After Completing Cancer Treatment Funding Agency: Alex's Lemonade Stand Project Dates: 2010 to 2012 Role: Principal Investigator Overall goal: To explore the feasibility and benefits of a six session, weekly yoga intervention for pediatric cancer survivors who completed therapy in the past two months to two years

Title: Fatigue, Physical Activity, and Carnitine Plasma Levels in Children Receiving Chemotherapy Funding Agency: The American Cancer Society Doctoral Nursing Scholarship; The Center for Children with Special Health Care Needs, Leadership in Nursing grant number T80-MC00010, from the Maternal and Child Health Bureau, Health Resources and Services; The White Family Oncology Fellowship; The Oncology Nursing Society Foundation Doctoral Scholarship; and The Pine Tree Apple Tennis Classic Foundation. Project Dates: 2004-2009 Role: Principal Investigator Overall goal: To examine relationship between fatigue, physical performance, and carnitine among children (ages 6-12 years) and adolescents (ages 13-17 years) undergoing chemotherapy treatment for cancer.

Title of Project: Fatigue and Carnitine Plasma Levels over Eight Cycles of Chemotherapy Funding Agency: Alex's Lemonade Stand Project Dates: 2008-2010 Role: Co-investigator Overall goal: To explore carnitine as a physiologic marker for fatigue in children and adolescents receiving cancer chemotherapy

Title of Project: Motor Performance and Fatigue in Children and Teens After Treatment for Acute Lymphoblastic Leukemia Funding Agency: Pine Tree Apple Tennis Classic Project Dates: 2005 -2011 Role: Co-investigator Overall goal: To evaluate the long- term, off therapy outcomes of children and adolescents who received the Stoplight Program intervention during treatment for ALL

Title of Project: Symptom Clusters in Children/Adolescents on Cisplatin, Ifosphamide, or Doxorubicin Funding Agency: Oncology Nursing Foundation Project Dates: 2004-2008 Role: Co-investigator Overall goal: To examine the influence of the proposed symptom cluster of fatigue, nausea and vomiting and sleep disturbances on clinical outcomes defined as behavior changes, depression and performance status in children and adolescents before and after receiving cisplatin, ifosfamide, or doxorubicin chemotherapy.

Publications

Selected Publications:

  • Jacobson, K., & Hooke, M. C. (in press). Telehealth Videoconferencing for Children With Hemophilia and Their Families A Clinical Project. Journal of Pediatric Oncology Nursing.
  • Hooke, M. C., Gilchrist, L., Tanner, L., Hart, N., & Withycombe, J. S. (2016).Use of a Fitness Tracker to Promote Physical Activity in Children With Acute Lymphoblastic Leukemia. Pediatric Blood & Cancer, 63(4), 684-689.
  • Herriage, T., Hooke, M. C., Streifel, A., & Slaker, B. (2016). Utilization of an Intravenous Line Lifter Within a Pediatric Oncology Population. Journal of Pediatric Oncology Nursing, 33(2), 105-110.
  • Gil, S., Hooke, M. C., & Niess, D. (2016).The Limited English Proficiency Patient Family Advocate Role Fostering Respectful and Effective Care Across Language and Culture in a Pediatric Oncology Setting. Journal of Pediatric Oncology Nursing, 33(3), 190-198
  • Hooke, M.C., Gilchrist, L., Foster, L., Langevin, M., & Lee, J. (2016). Yoga for children and adolescents after completing cancer treatment. Journal of Pediatric Oncology Nursing, 33(1),64-73.
  • Hooke, M. C. & Haase, J. E. (2015). Introduction; Adolescents and Young Adults with Cancer. Seminars in Oncology Nursing, 31(3), 183-185.
  • Macpherson, C. F., Hooke, M. C., Friedman, D. L., Campbell, K., Withycombe, J., Schwartz, C. L., ...& Meza, J. (2015). Exercise and Fatigue in Adolescent and Young Adult Survivors of Hodgkin Lymphoma: A Report from the Children's Oncology Group. Journal of Adolescent and Young Adult Oncology, 4(3), 137-140.
  • Tanner, L., Hooke, M.C., Hansen, C., & Hinshon, S. (2015). Impact of an Ankle Foot Orthosis Intervention in Children with non-CNS Cancers: A Pilot Study. Pediatric Physical Therapy, 27(4), 425-431.
  • Hooke, M. C., Hockenberry, M. J., McCarthy, K., & Taylor, O. (2014).Fatigue and Carnitine Levels over Multiple Cycles of Chemotherapy in Children and Adolescents. European Journal of Oncology Nursing.
  • Felgenhauer, J. & Hooke, M.C. (2014).Regulatory barriers to clinical trial enrollment of adolescent and young adult oncology patients. Pediatrics, 133 Suppl3, S119-122.
  • Kelly K.P., Hooke, M.C., Ruccione, K.S., Landier, W., & Haase, J.(2014).Developing an organizing framework to guide nursing research in the Children’s Oncology Group (COG): The enduring legacy of a nursing scholar program after merger of the pediatric cooperative groups. Seminars in Oncology Nursing, 30(1), 17-25.
  • Hooke, M.C., Garwick, A.W., & Neglia, J.P. (2013). Assessment of physical performance using the 6- Minute Walk Test in children receiving treatment for cancer. Cancer Nursing. 36(5), E9-E16.
    Rodgers, C.C., Hooke, M.C., & Hockenberry, M.J. (2013). Symptom clusters in children. Current Opinion in Supportive & Palliative Care. 7(1), 67-72.
  • Reeve, B.B., Withycombe, J.S., Baker, J.N., Hooke, M.C., Lyons, J.C., Mowbray, C., et al…. Hinds, P.S. (2013). The first step to integrating the child’s voice in adverse event reporting in oncology trials: a content validation study among pediatric oncology clinicians. Pediatric Blood & Cancer. 60(7), 1231-1236.
  • Fernandez, C., Ruccione, K., Wells, R., Long, J., Pelletier, W., Hooke, M. C., et al…. Joffe, S. (2012). Recommendations for the return of research results to study participants and guardians: A report from the Children’s Oncology Group. Journal of Clinical Oncology, 30(36), 4573-4579.
  • Hooke, M. C., Garwick, A. W. & Gross, C. P. (2011). Fatigue and physical performance in children and adolescents receiving chemotherapy. Oncology Nursing Forum, 83(6), 649-657.
  • Mandrell, B., Yang, J., Hooke, M. C., Wang, C., Gattuso, J.S., Hockenberry, M. Hinds, P.S. (2011). Psychometric and clinical assessment of the 13-item reduced version of the Fatigue Scale-Adolescent instrument. Journal of Pediatric Oncology Nursing, 28(5), 287-294.
  • Hockenberry, M.J., Hooke, M. C., McCarthy, K., Gregurich, M.A. (2111). Sickness behavior clustering in children with cancer. Journal of Pediatric Oncology Nursing, 28(5), 263-272. 
  • Gorlin, J.B., Hooke, M. C., & Leonard, N. (2011). Use of emergency medical identification in the paediatric haemophilia population: a national study. Haemophilia, 17(2), 215-222.
  • Hooke, M. C., Garwick, A. W. & Gross, C. P. (2011). Fatigue and physical performance in children and adolescents receiving chemotherapy. Oncology Nursing Forum, 83(6),649-657.
  • Hooke, M.C., MacPherson, C. F., Freyer, D.R. (2011). Adolescent and young adults with cancer: recognizing and responding to the challenges. www.PEDIATRICNPPA.com, 2(1), 20-32.
  • Thygeson, M. V., Hooke, M. C., Clapsaddle, J., Robbins, A., & Moquist, K. (2010). Peaceful play yoga: serenity and balance for children with cancer and their parents. Journal of Pediatric Oncology Nursing, 27(5), 276-284.
  • Hockenberry, M. J., Hooke, M. C., Gregurich, M., McCarthy, K., Sambuco, G.., & Krull, K. 2010. Symptom clusters in children and adolescents receiving cisplatin, ifosfamide, or doxorubicin. Oncology Nursing Forum, 37(1), E16-E27.
  • Hockenberry, M. J., Hooke, M. C., Gregurich, M., & McCarthy, K. 2009. Carnitine plasma levels and fatigue in children/adolescents receiving cisplatin, ifosfamide, or doxorubicin. Journal of Pediatric Hematology/Oncology. 31(9), 664-669.
  • Post-White, J., Fitzgerald, M., Savik, K., Hooke, M. C., Hannahan, A. B., & Sencer, S. F. (2009). Massage therapy for children with cancer. Journal of Pediatric Oncology Nursing, 26(1), 16-28.
  • Gilchrist L.S., Tanner L., Hooke M. C. (2009) Measuring Chemotherapy-Induced Peripheral Neuropathy in Children: Development of the Ped-mTNS and Pilot Study Results. Rehabilation Oncology, 27(3), 7-15.
  • Hockenberry, M. J. & Hooke, M. C. (2007) Symptom clusters in children with cancer. Seminars in Oncology Nursing. 23 (2), 152-157.
  • Hooke, M. C., Grund, H., Quammen, H., Miller, B., McCormick, P., & Bostrom, B. (2007) Propofol Use In Pediatric Patients with Severe Cancer Pain at the End of Life. Journal of Pediatric Oncology Nursing, 24, 29-34.

Book Chapters:

  • Hooke, M.C., Baggott, C., Robinson, D., Antill, M., Maloney, A. M., Madsen, L. (2012). Management of disease and treatment-related complications. In C. R. Baggott, K. P. Kelly, D. Fochtman, & G. V. Foley (Eds.) Nursing Care of Children and Adolescents with Cancer and Blood Disorders (4th ed.) (pp. 510-584). Glenview, IL: Association of Pediatric Hematology/Oncology Nurses.
  • Association of Pediatric Hematology/Oncology Nurses, Nelson, M. B., Forte, K., Freiburg, D., Hooke, M. C., Kelly, K. P., Brace O’Neill, J. (2007). Pediatric Oncology Nursing: Scope and Standards of Practice. Glenview, IL: Association of Pediatric Hematology/Oncology Nurses.
  • Hooke, M. C. (2008). Psychosocial issues. In N. Kline (Ed.), The Pediatric Chemotherapy and Biotherapy Curriculum. (2nd ed.). Association of Pediatric Hematology/Oncology Nurses.